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They also provide greater convenience and adherence for those unwilling to self-inject

For patients who are needle-averse, who have difficulty adhering to strict dosing windows, or whose weight management goals do not require reductions of 20% or more, an oral GLP-1 weight loss regimen may be a well-matched and more sustainable choice

J Diabetes Metab Disord 24 , 253 (2025)

10.1016/j.dsx.2021.03.010 21 DenkerP

GLP-1 medications, such as semaglutide and tirzepatide, mimic the action of the hormone GLP-1 in the body, helping to regulate appetite, blood sugar levels, and promote feelings of fullness after meals

The research also found that people living with health inequities or those who live in underserved areas were least likely to continue treatment
